Clarithromycin ( Biaxin) is a ivory to off-white crystalline powder. It is soluble in acetone, slight soluble in methanol, ethanol, and acetonitrile, and to all intents insoluble in water.
BIAXIN is convenient as immediate-release tablets, extended-release tablets, and granules for the sake of verbal suspension
Each yellow oval film-coated immediate-release BIAXIN plaque (clarithromycin tablets, USP) contains 250 mg or 500 mg of clarithromycin and the following still ingredients:
250 mg tablets: hypromellose, hydroxypropyl cellulose, croscarmellose sodium, D&C Yellow No. 10, FD&C Blue No. 1, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, propylene glycol, silicon dioxide, sorbic acid, sorbitan monooleate, stearic acid, talc, titanium dioxide, and vanillin.
500 mg tablets: hypromellose, hydroxypropyl cellulose, colloidal silicon dioxide, croscarmellose sodium, D&C Yellow No. 10, magnesium stearate, microcrystalline cellulose, povidone, propylene glycol, sorbic acid, sorbitan monooleate, titanium dioxide, and vanillin.
Each yellow oval film-coated BIAXIN XL writing- (clarithromycin extended-release tablets) contains 500 mg of clarithromycin and the following listless ingredients: cellulosic polymers, D&C Yellow No. 10, lactose monohydrate, magnesium stearate, propylene glycol, sorbic acid, sorbitan monooleate, talc, titanium dioxide, and vanillin.
After constitution, each 5 mL of BIAXIN discontinuing (clarithromycin seeking viva voce moratorium, USP) contains 125 mg or 250 mg of clarithromycin. Each flask of BIAXIN granules contains 1250 mg (50 mL evaluate), 2500 mg (50 and 100 mL sizes) or 5000 mg (100 mL volume) of clarithromycin and the following idle ingredients: carbomer, castor lubricate, citric acid, hypromellose phthalate, maltodextrin, potassium sorbate, povidone, silicon dioxide, sucrose, xanthan gum, titanium dioxide and fruit power flavor.
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